Amiglyde-V

529.50 Amikacin sulfate intrauterine solution.

Specifications: Each milliliter of sterile aqueous solution contains 250 milligrams of amikacin (as the sulfate).

Conditions of use:

Horses (mares)

Amount: Two grams (8 milliliters) diluted with 200 milliliters of sterile physiological saline per day for 3 consecutive days.

Indications: For treating genital tract infections (endometritis, metritis, and pyometra) in mares when caused by susceptible organisms including E. coli, Pseudomonas species, and Klebsiella species.

Limitations: For intrauterine infusion in the horse only. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

522.56 Amikacin sulfate injection.

Specifications: Each milliliter of sterile aqueous solution contains 50 milligrams of amikacin (as the sulfate).

Conditions of use:

Dogs

Amount: 5 milligrams per pound of body weight twice daily.

Indications: The drug is used in dogs for treatment of genitourinary tract infections (cystitis) caused by susceptible strains of Escherichia coli and Proteus species and skin and soft tissue infections caused by susceptible strains of Pseudomonas species and E. coli.

Limitations: The drug is administered intramuscularly or subcutaneously. Treat dogs with skin and soft tissue infections for a minimum of 7 days and those with genitourinary infections for 78 to 21 days or until culture is negative and asymptomatic. If no response is observed after 3 days of treatment, therapy should be discontinued and the case reevaluated. Maximum duration of therapy should not exceed 30 days. Systemic aminoglycoside therapy is contraindicated in dogs with seriously impaired renal function. Not for use in breeding dogs as reproductive studies have not been conducted. Use with extreme caution in dogs in which hearing acuity is required for functioning. Federal law restricts this drug to use by or on the order of a licensed veterinarian.