ANADA Number: 200-130

Proprietary Name Neo-Sol 50®
Sponsor Alpharma, Inc.
Sponsor Address 440 Rte. 22
Bridgewater, NJ    08807
USA
Ingredients Neomycin Sulfate
Species Cattle, excluding veal calves
Turkey, growing
Goat, no use class stated or implied
Sheep, no use class stated or implied
Swine, no use class stated or implied
Routes of Administration Per Os
Dose Form Liquid (solution)
Drug Form Liquid (solution)
This Document (200-130) Was Pioneered By:     Pharmacia & Upjohn Co.
Dispensing Status OTC
Withdrawal Time Cattle excluding veal calves: 1 day before slaughter. Goats: 3 days before slaughter. Swine: 3 days before slaughter. Sheep: 2 days before slaughter. Turkey: zero days before slaughter.
Dosage Amount,
Indications
& Limitations

520.1484 Neomycin sulfate soluble powder.

Specifications: The drug contains 20.3 grams of neomycin sulfate per ounce which is equivalent to 14.2 grams of neomycin base.

Conditions of use:

Cattle (excluding veal calves)

Amount: 10 milligrams of neomycin sulfate per pound of body weight per day in divided doses for a maximum of 14 days.

Indications: For the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate.

Limitations: Add to drinking water or milk. Not for use in liquid supplements. Prepare a fresh solution daily. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days. Discontinue treatment 1 day before slaughter.

Swine

Amount: 10 milligrams of neomycin sulfate per pound of body weight per day in divided doses for a maximum of 14 days.

Indications: For the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate.

Limitations: Add to drinking water or milk. Not for use in liquid supplements. Prepare a fresh solution daily. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days. Discontinue treatment 3 days before slaughter.

Sheep

Amount: 10 milligrams of neomycin sulfate per pound of body weight per day in divided doses for a maximum of 14 days.

Indications: For the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate.

Limitations: Add to drinking water or milk. Not for use in liquid supplements. Prepare a fresh solution daily. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days. Discontinue treatment 2 days before slaughter.

Goats

Amount: 10 milligrams of neomycin sulfate per pound of body weight per day in divided doses for a maximum of 14 days.

Indications: For the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate.

Limitations: Add to drinking water or milk. Not for use in liquid supplements. Prepare a fresh solution daily. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days. Discontinue treatment 3 days before slaughter.

Turkeys (growing)

Amount: 10 milligrams of neomycin sulfate per pound of body weight per day (22 milligrams per kilogram) for 5 days.

Indications: For the control of mortality associated with E. coli organisms susceptible to neomycin sulfate in growing turkeys.

Limitations: Add to drinking water. Not for use in liquid supplements. Prepare a fresh solution daily. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 5 consecutive days.

Tolerances

Tolerances are established for residues of parent neomycin in uncooked edible tissues as follows:

a. In cattle, swine, sheep, and goats: 7.2 parts per million in kidney (target tissue) and fat, 3.6 ppm in liver, and 1.2 ppm in muscle.

b. In turkeys: 7.2 ppm in skin with adhering fat, 3.6 parts per million in liver, and 1.2 ppm in muscle.

c. In milk: 0.15 part per million.