Complete Up To Date Information about Sustain III Bolus.
NADA Number: 120-615 | |
| Proprietary Name |
Sustain III® Bolus |
|---|---|
| Sponsor |
Cross Vetpharm Group Ltd. |
| Sponsor Address |
Broomhill rd. Tallaght, Dublin, 24 IRELAND |
| Ingredients |
Sulfamethazine |
| Species |
Cattle, dairy, not lactating Cattle, beef Cattle, calves, ruminating |
| Routes of Administration |
Per Os |
| Dose Form |
Sustained release bolus |
| Drug Form |
Sustained release bolus |
| Dispensing Status |
OTC |
| Withdrawal Time |
Cattle: 12 days before slaughter. |
|
Dosage Amount, Indications & Limitations |
520.2260b Sulfamethazine sustained-release boluses. Specifications: 32.1-gram sustained-release bolus. Conditions of use: Cattle (beef and nonlactating dairy) Amount: 32.1 grams (1 bolus) per 200 pounds of body weight. Indications: For beef and nonlactating dairy cattle for the treatment of diseases caused by sulfamethazine-sensitive organisms as follows: bacterial pneumonia and bovine respiratory disease complex (shipping fever complex) caused by Pasteurella species, colibacillosis (bacterial scours) caused by E. coli, necrotic pododermatitis (foot rot) and calf diphtheria caused by Fusobacterium necrophorum, and acute mastitis and acute metritis caused by Streptococcus species) Limitations: After 72 hours, all animals should be reexamined for persistence of observable disease signs. If signs are present, consult a veterinarian. It is strongly recommended that a second dose be given to provide for an additional 72 hours of therapy, particularly in severe cases. The dosage schedule should be used at each 72-hour interval. Animals should not receive more than 2 doses because of the possibility of incurring residue violations. This drug, like all sulfonamides, may cause toxic reactions and irreparable injury unless administered with adequate and continuous supervision; follow dosages carefully. Fluid intake must be adequate at all times throughout the 3-day therapy, Do not use in lactating dairy cattle. Do not treat animals within 12 days of slaughter. NAS/NRC status: These conditions are NAS/NRC reviewed and found effective. Applications for these uses need not include effectiveness data as specified by 514.111 of this chapter, but may require bioequivalency and safety information. Specifications: 8.02-gram sulfamethazine sustained-release bolus. Conditions of use: Amount: Administer 2 boluses (8.02 grams per bolus) per 100 pounds of body weight, as a single dose. Indications: Administer orally to ruminating calves for the prolonged treatment of the following diseases when caused by one or more of the listed pathogenic organisms sensitive to sulfamethazine: bacterial pneumonia (Pasteurella species), colibacillosis (bacterial scours) (E. coli), and calf diphtheria (Fusobacterium necrophorum). Limitations: For use in ruminating replacement calves only. 72 hours after dosing all animals should be reexamined for persistence of disease signs. If signs are present, consult a veterinarian. Do not slaughter animals for food for at least 12 days after the last dose. This product has not been shown to be effective for nonruminating calves. Exceeding two consecutive doses may cause violative tissue residue to remain beyond the withdrawal time. Do not use in calves under 1 month of age or calves being fed an all milk diet. |
| Tolerances |
A tolerance of 0.1 part per million is established for negligible residues of sulfamethazine in the uncooked edible tissues of chickens, turkeys, cattle, and swine. |