NADA Number: 141-043

Proprietary Name Synovex® Plus
Synovex® Choice
Sponsor Fort Dodge Animal Health, Division of Wyeth
Sponsor Address 800 Fifth Street NW
Fort Dodge, IA    50501
USA
Ingredients Estradiol Benzoate
Trenbolone Acetate
Species Cattle, beef, heifers fed in confinement for slaughter excluding veal
Cattle, beef, steers fed in confinement for slaughter, excluding veal
Routes of Administration Subcutaneous
Dose Form Implant (pellet)
Drug Form Implant (pellet)
Dispensing Status OTC
Exclusivity Granted for use in steers fed in confinement at a new dosing level of 100 mg trenbolone acetate and 14 mg estradiol benzoate per implant.
Granted for increased rate of weight gain in confined steers.
Granted for use as an ear implants in steers fed in confinement to improve feed efficiency.
Granted for a new class of cattle (heifers) for increased rate of weight gain and improved feed efficiency.
Withdrawal Time Cattle: zero days before slaughter
Dosage Amount,
Indications
& Limitations

522.2478 Trenbolone acetate and estradiol benzoate.

Specifications: Each implant dose consists of: 8 pellets, each pellet containing 25 milligrams trenbolone acetate and 3.5 mg estradiol benzoate. Each implant dose consists of: 4 pellets, each pellet containing 25 mg trenbolone acetate and 3.5 mg estradiol benzoate.

Conditions of use:

Cattle (steers fed in confinement for slaughter excluding veal)

Amount: 200 mg trenbolone acetate and 28 mg estradiol benzoate.

Indications: Implant subcutaneously in ear only. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.

Limitations: Implant subcutaneously in ear only.

Amount. 100 mg trenbolone acetate and 14 mg estradiol benzoate.

Indications: For increased rate of weight gain.

Limitations. Implant subcutaneously in ear only.

Cattle (heifers fed in confinement for slaughter excluding veal)

Amount: 200 mg trenbolone acetate and 28 mg estradiol benzoate.

Indications: For increased rate of weight gain.

Limitations: Implant subcutaneously in ear only. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.

Tolerances

A tolerance for total trenbolone residues in uncooked edible tissues of cattle is not needed.

No residues of estradiol, resulting from the use of estradiol or any of the related esters, are permitted in excess of the following increments above the concentrations of estradiol naturally present in untreated animals:

a. In uncooked edible tissues of heifers, steers, and calves: (1) 120 parts per trillion for muscle (2) 480 parts per trillion for fat (3) 360 parts per trillion for kidney (4) 240 parts per trillion for liver

b. In uncooked edible tissues of lambs: (1) 120 parts per trillion for muscle (2) 600 parts per trillion for fat, kidney, and liver